MD-Gem
The Maryland Genetics, Epidemiology, and Medicine Training Program

Genetic Epidemiology - Students

Shan Andrews

I am primarily interested in methods for and applications of DNA methylation (DNAm), particularly as applied to Autism Spectrum Disorder (ASD). My work has focused on parsing technical and biological signal from the Illumina 450K Array, specifically in the characterization of multimodal distributions of DNAm signal. I have also worked on understanding the role of SNPs and haplotypes in DNAm (and as applied to ASD), and the extent of blood-brain DNAm concordance in ASD.

Samantha Bomotti

I earned a MPH in Epidemiology with a Certificate in Public Health Genetics at the University of Michigan School of Public Health, from which I graduated in 2013. My continued interest in genetics led me to apply to the Genetic Epidemiology PhD program at Johns Hopkins Bloomberg School of Public Health. I am a trainee on the NEI T32 Statistical Genetics of Ocular Disorders training grant.

Entered Program: 2013

Fei Chen

My primary interests are in genetics of pancreatic cancer and their interactions with environmental risk factors including smoking and alcohol. My dissertation is aimed to understand the genetic connections between chronic pancreatitis, diabetes and pancreatic cancer. I am also working on exome array and exome sequencing data of eye diseases and infectious diseases, conducing linkage and association analysis in population and family-based cohorts.

Michael Chou

Woori Kim

Weiyan Li

I am interested in how genetics affects complex human diseases on its own and by gene-environment interaction. I am particularly interested in studying epigenetics as the intermediate layer between genes and environment. Also, I have an interest in early life exposures, especially how it may impact disease onset later in life through genetic, epigenetic or other mechanisms.

Entered Program: 2013

Stephanie Loomis

I’m interested in using genetic epi to explore the molecular mechanisms of disease, particularly disease such as diabetes, which have both strong genetic and environmental causes.

Rebecca Mitchell

The focus of my research is on variation in mitochondrial DNA, including mtDNA copy number, heteroplasmy, and inherited genetic variation. I have been investigating the association of this variation with epigenetic modifications, specifically methylation, and the effect of this variation on physical function and aging-related disease (such as phenotypes associated with reduced mtDNA copy number).

Norazlin Kamal Nor

My research interest is tin developmental psychopathology, autism spectrum disorders and child health, development and protection.

Entered Program: 2013

Johanna Robertson

Johanna is an MD-Gem fellow in the Human Genetics program at Johns Hopkins School of Medicine. In our lab, Johanna has helped to pioneer and optimize the use of single cell RNA-Seq technologies and is involved in projects as diverse as neuronal subtype characterization in combination with retrograde labeling, single cell RNA-Seq characterization of somatic mosaic variation in primary patient cells, and iPSC modeling of neurogenic disorders. Her current project involves characterization of the genotype-phenotype relationship for neurogenesis defects in several disorders of the epigenetic machinery.

Brooke Sheppard

I am interested in genetic etiology of psychiatric disorders.  I am currently working on a pre-doc fellowship with the Section for Developmental Genetic Epidemiology of NIMH, researching environmental and genetic correlates of autism spectrum disorder and other neurodevelopmental conditions.

Entered Program: 2012

Kelly Bakulski

Kelly Bakulski joined the JHSPH genetic epidemiology group in 2013 as a post doctoral research fellow working with Dani Fallin and Andy Feinberg. Kelly's research focuses on environmental and genetic risk factors for autism spectrum disorders and the potential influence of the perinatal DNA methylome. She integrates molecular epidemiology, exposure assessment, nutrition, and genomics to better understand disease susceptibility through her work with the Early Autism Risk Longitudinal Investigation (EARLI) network.

Kelly received her Ph.D. from the University of Michigan School of Public Health Department of Environmental Health Sciences in 2012, where she studied the epigenetics of late-onset Alzheimer's disease as well as heavy metal exposure risk factors for cognitive decline.

Ferdouse Begum

I am a postdoctoral fellow in the Department of Epidemiology at Johns Hopkins Bloomberg School of public Health. Currently I am involved with different collaborative studies on genetic epidemiology of oral cleft and a study of chronic obstructive pulmonary disease. My area of research is statistical genetics. My primary objective is to develop statistical  and computational methods for different types of high-throughput genomics data including targeted sequencing data, whole exome sequencing data and whole genome sequencing data. My mentors are Dr. Terri Beaty and Dr. Ingo Ruczinski.

Doctoral Students (Click on an individual for more information)
Shan Andrews Photo

Shan Andrews

Samantha Bomotti Photo

Samantha Bomotti

Fei Chen Photo

Fei Chen

Michael Chou Photo

Michael Chou

Woori Kim Photo

Woori Kim

Weiyan Li Photo

Weiyan Li

Stephanie Loomis Photo

Stephanie Loomis

Rebecca Mitchell Photo

Rebecca Mitchell

Norazlin Kamal Nor Photo

Norazlin Kamal Nor

Johanna Robertson Photo

Johanna Robertson

Brooke Sheppard Photo

Brooke Sheppard

Masters Students
Tyler Bryant Photo

Tyler Bryant

Entered Program: 2015
Tara Dhingra Photo

Tara Dhingra

Entered Program: 2014
Zoe Packman Photo

Zoe Packman

Entered Program: 2015
Post-Doc Students (Click on an individual for more information)
Kelly Bakulski Photo

Kelly Bakulski

Ferdouse Begum Photo

Ferdouse Begum

Sampling of Former Students
Doctorate
Name Degree Year Research Project Current Position
Man Li PhD 2015 Understanding the genetic architecture of kidney function through analysis of genome-wide arrays Postdoc Fellow at Johns Hopkins Bloomberg School of Public Health (PI: Josef Coresh); Postdoc Fellow at University of Utah Departments of Nephrology and Human Genetics (PI: Alfred Cheung, Mark Yan)
Margaret Parker PhD 2015 Exome array analysis of pulmonary function in smokers with and without chronic obstructive pulmonary disease Postdoctoral Research Fellow, Channing Division of Network Medicine at Brigham and Women's Hospital Research Fellow, Harvard Medical School
Poojitha Balakrishnan PhD 2015 Determinants of Blood Pressure Trajectories: the Atherosclerosis Risk In Communities (ARIC) Study Postdoctoral Fellow, Dr. Ana Navas-Acien, Johns Hopkins School of Public Health
Corinne Keet PhD 2014 Assistant Professor, JHMI
Genevieve Wojcik PhD 2013 Genomics of OPV response in Bangladeshi Children Post-Doc Stanford University, PI: Carlos Bustamante
Matthew Gribble PhD 2013 Arsenic Exposure, Arsenic Metabolism and Diabetes in the Strong Heart Post-Doc USC PI: Duncan Thomas
Asieh Golozar PhD 2012 Candidate Inflammation-related Genes and Esophageal Squamous Cell Carcinoma Research Associate Department of Epidemiology JHSPH
Dana Behneman PhD 2012 “Fine-Mapping linkage and family-based association of familial idiopathic scoliosis and chromosome 1”. (co-advisor with A.F. Wilson) Teacher
Adrienne Tin PhD 2012 Research topic to be determined; possibly investigating genetic and environmental predictors of type 2 diabetes or metabolic syndrome Post-doctoral fellow Department of Epidemiology JHSPH PI: Linda Kao
Tao Wu PhD 2011 Candidate genes for oral clefts: Testing for gene-environment interaction in Chinese case-parent trios Associate Professor, Peking University Health Science Center, Beijing, China
Andrew Jaffe PhD 2010 Incorporating High-Throughput DNA Methylation Data in Epidemiological Studies Investigator Lieber Institute for Brain Development
Bhoom Suktitpat PhD 2010 GWAS of inflammatory Markers in the GeneStar Study Instructor Department of Biochemistry Faculty of Medicine Siriraj Hospital
Katherine Bowers PhD 2009 Oxidative Stress Pathway and Autism Assistant Professor Department of Pediatrics University of Cincinnati
Kelly Benke PhD 2009 lL1 genotypes and cognitive trajectories Post-Doc JHSPH PI: Brion Maher
Ching-Yu Cheng PhD 2008 Searching for human obesity genes by linkage and admixture mapping Assistant Professor, National Singapore University
Yu-Ching Cheng PhD 2008 Genetic Epidemiology of inflammatory responses to high fat diet and aspirin Assistant Professor, Division of Endocrinology, Diabetes and Nutrition, School of Medicine, The University of Maryland
Edwina Yeung PhD 2008 Family history of coronary heart disease and the risk of type 2 diabetes; The effects of weight loss and macronutrient intake independent of weight loss on serum adiponectin levels Tenure-track Investigator, NIH, National Institute of Child Health and Human Development, Epidemiology Branch
Audrey Chu PhD 2008 Characterization of Type 2 Diabetes Mellitus Susceptibility Genes and their Interactions with Environmental Risk Factors in the Population Post-doctoral fellow, Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School
Adam Naj PhD 2008 Genetic Determinants of Type 2 Diabetes Mellitus and Related Endophenotypes in the Old Order Amish Assistant Professor, University of Pennsylvania
Amy Mahoney Matteini PhD 2007 Homocysteine and Frailty Research Associate Division of Geriatric Medicince and Geronotology JHMI
Audrey Grant PhD 2007 Genetic factors influencing immunoglobulin E levels and burden of Schistosoma mansoni infection in an endemic population in Brazil. Human Genetics of Infectious Diseases, INSERM / Université Paris Descartes
Masters
Name Degree Year Research Project Current Position
Jennifer Wang ScM 2015 A genome-wide association study of survival in head and neck squamous cell carcinoma
Yanzi Xiao ScM 2015 Detecting Gene-Gene Interactions for Cleft Lip with/without Cleft Palate in Targeted Sequencing Data Data Analyst at the Division of Cancer Epidemiology and Genetics at NCI
Stephanie Williams ScM 2012 Associations of 16p 11.2 CNVs with Autism: Communication and Family understand of Risk Statistical Analyst, Genetics Department at UNC
Tian Xiao Zhang ScM 2011 Pathway analysis in a case-parent trio study of oral clefts PhD Student, Washington Univeristy
Tiffany Green MHS 2011 The Heritability of Immunoglobulin Response to Schistosoma mansoni Infection in a Rural Brazilian Community Program Analyst, National Cancer Institute, NIH
Rehan Qayyum MHS 2010 Genetic Determinants of Subclinical Coronary Artery Disease as measured by Stress Thallium Scan
Patel Poorav MHS 2010 X-Linked Genetic Factors Associated with Oral Facial Cleft Phenotypes. (co-advisor with M.D. Fallin) Medical Student Oregon Health & Science University
Tanda Murray MHS 2008 Using genome wide SNPs to characterize admixture in African Americans and an African Caribbean MD/PhD Student, Mayo Clinic
Evaristus Nwulia MHS 2008 Genome-wide analysis of alcohol dependence subphenotype of bipolar disorder. Assistant Professor Director Psychiatric Neuroscience Laboratory Howard University
Roxann Ashworth MHS 2007 Association between genes on chromosome 4p16 and non-syndromic cleft lip and/or cleft palate Director, Sanger Sequencing and Real-Time PCR Laboratory JHMI